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EINE SICHERE UND BEWÄHRTE


           KOLLEKTION VON FILLERN


           IN-VITRO- UND KLINISCHE STUDIEN



          GUTES SICHERHEITS- UND VERTRÄGLICHKEITSPROFIL                                  (5)



          ADVERSE EVENT AT D0 AFTER INJECTION
                                                                        Die Anzahl der Fälle von Nebenwirkungen
                                                                       ist geringer als bei der Marktreferenz.
                                                                                                    ®
                                                                       Außerdem sind bei ART FILLER  VOLUME
                                                                      die inflammatorischen Reaktionen
                                                                      deutlich geringer im Vergleich zur
                                                                      Marktreferenz.

                                                                    (EXPRESSION VON ENTZÜNDUNGSMARKERN IN DER
                                                                    KUTANEN EX-VIVO MIKRODIALYSE)










          STUDIEN UND VERÖFFENTLICHUNGEN



                                            GOX.0000000000003274. PMID: 33425589; PMCID:   skin aging parameters. Fanian F, Philippon V, Gorj
                                            PMC7787280.                        M, Rumyantseva Mathey E,Caillens M, Goorochurn R,
                                                                               Curic S, Humbert P. Clin Cosmet Investig Dermatol.
                                            Comparative clinical study for the efficacy and safety   2023;16:1095-1105  https://doi.org/10.2147/CCID.
          Prospective, split-face, randomized, long-term   of two different hyaluronic acid-based fillers with   S372490.
                                                  ®
          blinded objective comparison of the performance   TRI-HYAL  versus Vycross technology: a long-term
          and tolerability of two new hyaluronic acid fillers.   prospective randomized clinical trial.  Braccini F,   Long-term efficacy and safety of a hyaluronic acid
                                                                                                     ®
          Trevidic P, Andre P, Benadiba L, Deutsch JJ, Galatoire   Fanian F, Garcia P, Delmar H, Loreto F, Benadiba   dermal filler based on TRI-HYAL  Technology on
          O, Garcia P, Grand-Vincent A, Boisnic S, Kerihuel JC,   L, Nadra K, Kestemont P. J Cosmet Dermatol. 2023   restoration of midface volume. Kestemont P, Fanian
          Salomon  C.  Dermatol  Surg.  2017  Dec;43(12):1448-  Feb;22(2):473-485. doi: 10.1111/jocd.15200. Epub   F, Garcia P, Grand-Vincent A, Benadiba L, Delmar H,
          1457. doi: 10.1097/DSS.0000000000001193. Erratum   2022 Jul 19. PMID: 35770300; PMCID: PMC10084174.  Bodokh I, Brun P, Braccini F, Desouches C, Paris J,
          in: Dermatol Surg. 2018 Aug;44(8):1158. PMID:                        Nadra K, Salomon C, Trevidic P. J Cosmet Dermatol.
          28595250.                         A prospective multicenter clinical trial evaluating   2023  Sep;22(9):2448-2456.  doi:  10.1111/jocd.15752.
                                            the  efficacy  and  safety  of  a  hyaluronic  acid-based   Epub 2023 May 2. PMID: 37128822.
                                                         ®
          Triple  cross-linked  hyaluronic  acid  based  on     filler with TRI-HYAL  Technology in the treatment of
          TRI-HYAL  technique has more durable effect on   lips and the peri-oral area. Ehlinger-David A, Gorj M,
                ®
          dermal renewal. Chen R, Yang W, Sun J, Liu Y, An   Braccini F, Loreto F, Grand-Vincent A, Garcia P, Taieb   SCANNEN, UM ALLE
          Q, Zhang F, Bai Z, Luan Q. Clin Cosmet Investig   M, Benadiba L, Catoni I, Mathey ER, Deutsch JJ,   VERÖFFENTLICHUNGEN ZU
          Dermatol. 2022;15:691-701 https://doi.org/10.2147/  Bahadoran P, Vincent T, David M, Cartier H, Nadra   SEHEN
          CCID.S362785.                     K, Moellhoff N, Fanian F.. J Cosmet Dermatol. 2023
                                            Feb;22(2):464-472. doi: 10.1111/jocd.15169. Epub
          A hyaluronic acid-based filler reduces lipolysis in   2022 Jul 31. PMID: 35718985; PMCID: PMC10087550.
          human mature adipocytes and maintains adherence
          and lipid accumulation of long-term differentiated   Long-term efficacy and tolerability of a medium
                                                               ®
          human preadipocytes. Nadra K, André M, Marchaud   g’  ha filler with  TRI-HYAL   Technology  on the
          E, Kestemont P, Braccini F, Cartier H, Kéophiphath M,   rejuvenation of the mobile facial zone.  David M,
          Fanian F. J Cosmet Dermatol. 2021 May;20(5):1474-  Braccini F, Garcia P, Loreto F, Benadiba L, Gorj M,
          1482.  doi: 10.1111/jocd.13794.  Epub 2020  Nov 4.   Grand-Vincent A, Rumyantseva Mathey E, Deutsch
          PMID: 33150734; PMCID: PMC8246837.  JJ, Ehlinger A, Cartier H, Nadra K, Fanian F. Clin
                                            Cosmet Investig Dermatol. 2023 Jul 13;16:1795-
          Objective 18-month comparison of the tolerability   1805. doi: 10.2147/CCID.S395353.  PMID: 37465030;
          of 2 dermal fillers formulated with TRI-HYAL    PMCID: PMC10351526.
                                         ®
          Technology.  Trevidic P, Andre P, Benadiba L,
          Deutsch JJ, Galatoire O, Garcia P, Grand-Vincent A,   Evaluation of the performance and tolerance
          Boisnic S, Salomon C, Fanian F. Plast Reconstr Surg   of  the  combination  of  an  HA-based  filler  with
                                                  ®
          Glob Open. 2020 Dec 9;8(12):e3274. doi: 10.1097/  TRI-HYAL  Technology and a skin biorevitalizer on
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